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Interesting. Something for the makers too to ponder 🙂 2 points:
1. If they are at a different focal length, go for a narrower aperture f/11 and above. You may get the whole scene in focus. However this may decrease shutter speed or boost up the ISO
2. If they are at the same focal length then it is relatively easy. Focus on one the other will be in focus automatically. Play with apertures to find ideal spot